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Srijana Shrestha

Srijana Shrestha

Kathmandu University, Nepal

Title: Cytological pattern of cervical pap smears in selected hospitals of Kathmandu, Nepal

Biography

Biography: Srijana Shrestha

Abstract

Background: Cervical cancer is one of the leading cause of morbidity and mortality. It can be preventable and diagnosed early with adequate and repetitive cytological screening by Pap test. The conventional cervical cytological screening is the most common technique used worldwide.

Material and Method: The present study is a retrospective study, carried out in  Total 1999 cases in two years period from Shrawan 2072 to Shrawan 2074.

Results : Out of 1999 smears, 56 cases (2.8%) were unsatisfactory/inadequate, 1884 (94.25%)smears were NILM (negative for intraepithelial lesion/malignancy), 115 (5.75%)smears showed epithelial cells abnormalities and 439(21.96%) smears were with   reactive cellular changes associated with inflammation . Bacterial vaginosis (55.35%) was the most common etiology identified in 439 cases of inflammatory smears.Total 310 (15.5%) cases showed moderate to severe atrophic changes in smear cytology.Among 18 follow up cases of carcinoma cervix, one case (0.2%) was identified as relapse case.

Conclusion: Bethesda system classification 2001 found to be very useful screening method for early detection of epithelial cells abnormalities of the cervix in Nepali population.As all the cases of epithelial cells abnormities were of age above 30 years, Pap smear examination shall begin in women at least at the age of 30 years.  Large studies are required to estimate the pattern of cervical cytological abnormalities along with Human papillomavirus (HPV) strain detection in Nepali population.