Jai Kumar Chaurasia
Head and Chief of Lab at Dr. Lalpathlabs, India
Title: Rosai–Dorfman Disease: Unusual Presentation and Diagnosis by Fine-Needle Aspiration Cytology
Biography
Biography: Jai Kumar Chaurasia
Abstract
Rosai–Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy is a rare non-neoplastic, self-limiting histiocytic proliferative disorder of unknown etiology that usually presents with painless bilateral cervical lymphadenopathy and show distinct cytological features. Retroperitoneal lymph node enlargement due to Rosai–Dorfman disease is unusual and is rarely reported in literature. It is a difficult diagnosis due to disease’s non-specific clinical, hematological, and radiological findings, often overlapping with other diseases. We report an unusual case of Rosai–Dorfman disease in a male patient who presented with diffuse abdominal pain and retroperitoneal lymphadenopathy and diagnosed on fine-needle aspiration cytology (FNAC). This case emphasizes that Rosai–Dorfman disease should always be considered in cases presenting with retroperitoneal lymphadenopathy and FNAC can be used as a reliable tool to establish the diagnosis, avoiding unnecessary excisional biopsy, aggressive intervention, and overtreatment.