Qing Kay Li
The Johns Hopkins University School of Medicine, USA
Title: Current concept in the new WHO classification of lung cancers, and its impacts on the cytological differential diagnosis of lung cancers
Biography
Biography: Qing Kay Li
Abstract
The new WHO classification of lung cancers has been published recently. Several concepts and guidelines have been incorporated into this new edition based on molecular characterizations of lung tumors and targeted therapies. Many improvements have already been made in the past decade due to the discovery of EGFR mutation and the innovation of new diagnostic techniques. The new WHO classification has a critical impact on the cytological practice. The cytological specimens commonly used in clinical diagnosis include: sputum, bronchial brushing and washing, bronchoalveolar lavage, transbronchial fine needle aspiration (TBNA), endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TBNA), and transthoracic CT- or ultrasound-guided fine needle aspiration. Familiarity with the new classification of lung cancers, cytomorphological features of respiratory specimens, and techniques of obtaining these samples are critical in order to make an accurate diagnosis. In addition, ancillary studies, including immunohistochemical studies and molecular tests, also play important roles in lung cancer classification. In this presentation, we will discuss the current concept of lung cancers, and the utility of ancillary tests, including immunohistochemistry and molecular test, in the classification of lung cancers.
